Sabrina Spencer

Dr. Sabrina Spencer Shares Cancer Research Expertise with the Office of Science and Technology Policy White House Cabinet Director Dr. Arati Prabhakar

Anonymous — Thu, 25 Jul 2024 01:22:11 +0000

Dr. Sabrina Spencer Shares Cancer Research Expertise with the Office of Science and Technology Policy White House Cabinet Director Dr. Arati Prabhakar Anonymous (not verified) Wed, 07/24/2024 - 19:22

White House Science Official Comes to CU Anschutz for Cancer Briefing, Moonshot Updates

Arati Prabhakar, PhD, and a panel of elected officials and CU leaders shared information on the fight against cancer.

Dr. Sabrina Spencer, a CU ��«��Ƶ Biochemistry Professor and CU Cancer Center member, recently presented her lab's cancer research to White House Cabinet member and Director of the Office of Science and Technology Policy, Arati Prabhakar, PhD. The Biden Cancer Moonshot event took place at CU Anschutz on July 17, 2024. Also in attendance were CU President Todd Saliman, CU Anschutz Chancellor Don Elliman, Lieutenant Governor of Colorado Dianne Primavera, Congresswoman Diana DeGette, Cancer Center Deputy Director James DeGregori, and several other Anschutz faculty and staff. Dr. Spencer described her work using fluorescent sensors and time-lapse imaging to film and track cancer cells over many days. As an example of the discoveries her CU ��«��Ƶ lab has made, she described the identification of rare cancer cells that can rewire in just 3 days to escape from cancer drugs meant to block proliferation. “We detect these rogue cells across multiple cancer types and multiple drugs, and think they are a general seed population for resistance mutations months to years later. We are therefore working to limit this cancer cell plasticity in the hopes of reducing cancer relapse in patients."

More Details Here

Photo (left - right): Sabrina Spencer, PhD, Professor, CU ��«��Ƶ Andi Dwyer, Director, Colorado Cancer Screening Center Director of the Office of Science and Technology Policy, Arati Prabhakar Sarah Reynolds, Nurse Navigator in GI Oncology, UCHealth.

Photos Courtesy: University of Colorado Anschutz Medical Campus

Off

Traditional

White

Chroma awards Prof. Sabrina Spencer, PhD the Anne Heidenthal Prize for Fluorescence Research

Anonymous — Thu, 18 Jul 2024 16:36:31 +0000

Chroma awards Prof. Sabrina Spencer, PhD the Anne Heidenthal Prize for Fluorescence Research Anonymous (not verified) Thu, 07/18/2024 - 10:36

From the Chroma Technology Website:

This year, Chroma Technology is happy to present the Anne Heidenthal Prize for Fluorescence Research award to Prof. Sabrina Spencer from the ��«��Ƶ. This annual international prize is awarded to a young scientist who has performed extraordinary research in the field of fluorescence imaging. Dr. Spencer was selected by the committee for her work on the regulation of cell-cycle progression and cell-cycle withdrawal, enabled by single-cell, time-lapse imaging and computational tracking of novel live-cell sensors, in particular her sensor for CDK2 activity. In her prize lecture, she described her latest discoveries on the mechanisms by which cells rapidly adapt to to the new class of CDK2 inhibitors, allowing completion of the cell-cycle. CDK2 is hyperactive in many cancers, and Dr. Spencer's imaging of the dynamics of CDK2 activity suggests how to best apply these therapeutics, which are now in clinical trials for several types of cancer.

“We trust the committee year after year to select a scientist worthy of supporting, and we couldn’t be happier with this year’s choice,” said Georg Draude, General Manager of the Chroma GmbH German branch and presenter of the Anne Heidentah Prize, “We look forward to following Dr. Spencer’s future work.”

The Anne Heidenthal Prize for Fluorescence Research was established in 2014 to honor the memory of Anne Heidenthal (1968-2010). Anne Heidenthal was an accomplished researcher with a Ph.D. in Cardiovascular research who played a very important role in Chroma’s history. Anne led the opening of Chroma’s first international sales office in Germany in 2006. In preparation, she spent two years in Vermont working at Chroma’s main facility in Bellows Falls to learn the business and become deeply knowledgeable about our products and operations. Her commitment and energy laid the foundation for our future success.

Off

Traditional

White

Biochemist wins $750k for novel cancer research

Anonymous — Wed, 03 Feb 2021 07:00:00 +0000

Biochemist wins $750k for novel cancer research Anonymous (not verified) Wed, 02/03/2021 - 00:00

Sabrina L. Spencer, assistant professor of biochemistry and member of the BioFrontiers Institute at the ��«��Ƶ, is one of five new winners of a 2021 Damon Runyon-Rachleff Innovation Award, the Damon Runyon Cancer Research Foundation announced recently. She is also one of seven new winners of the 2021 Emerging Leader Award from the Mark Foundation for Cancer Research.

Off

Traditional

White

Sabrina Spencer honored with a Provost Faculty Achievement Award

Anonymous — Mon, 10 Aug 2020 17:02:27 +0000

Sabrina Spencer honored with a Provost Faculty Achievement Award Anonymous (not verified) Mon, 08/10/2020 - 11:02

Congratulations to Biochemistry Professor Sabrina Spencer, recipient of a 2020 Provost Faculty Achievement Award!

From the Provost’s Letter:

“In selecting you for this award, the faculty committee pointed to the importance of your article published in the high-impact journal Science: Temporal integration of mitogen history in mother cells controls proliferation of daughter cells, which overturns the longstanding conventional paradigm of cell growth and more specifically, provides new insight into the proliferation-quiescence decision in mammalian cells. Members of the committee were deeply impressed by the rigor and attention to detail shown in your research, and noted it would be difficult to ask for better scholarship. This work has profound and far-reaching implications not only for revising our general understanding of cell biology, but also of cancer biomarkers and drug therapy.”

Congrats Sabrina!

Off

Traditional

White

To divide or not to divide? The mother cell may decide

Anonymous — Thu, 02 Apr 2020 06:00:00 +0000

To divide or not to divide? The mother cell may decide Anonymous (not verified) Thu, 04/02/2020 - 00:00

Published: April 2 , 2020 • By Kelsey Simpkins

When do cells decide to divide? For 40 years, the textbook answer has been that this decision occurs in the first phase of a cell’s existence – right after a mother cell divides to become daughter cells. But researchers at CU ��«��Ƶ have found that it’s actually the mother cell that determines if its daughter cells will divide

Off

Traditional

White

CU ��«��Ƶ attracts a record $631 million in annual research funding

Anonymous — Mon, 07 Oct 2019 13:32:32 +0000

CU ��«��Ƶ attracts a record $631 million in annual research funding Anonymous (not verified) Mon, 10/07/2019 - 07:32

CU ��«��Ƶ research attracted a record $631 million in funding in fiscal year 2019 for groundbreaking studies that investigate a changing environment, explore new opportunities in space, mitigate the effects of natural hazards, advance biomedical research and seek cleaner, more sustainable energy solutions.

Off

Traditional

White

Biochemist wins top award for study of cellular proliferation

Anonymous — Fri, 05 Oct 2018 14:33:01 +0000

Biochemist wins top award for study of cellular proliferation Anonymous (not verified) Fri, 10/05/2018 - 08:33

NIH’s High-Risk, High-Reward Research program to fund Sabrina Spencer’s CU ��«��Ƶ research that could shed light on cancer treatment

Scientists do not fully understand how cells choose between proliferation and quiescence (a state of non-proliferation) but a ��«��Ƶ biochemist’s novel proposal to study the issue has won the support of the National Institutes of Health (NIH).

Sabrina Spencer, CU ��«��Ƶ assistant professor of biochemistry, is one of 58 scientists nationwide to have won an NIH Director’s New Innovator Award. Those awards, announced today, are part of the High-Risk, High-Reward Research program, which supports “extraordinarily creative scientists proposing highly innovative research to address major challenges in biomedical research.” Zoe Donaldson, an assistant professor of behavioral neuroscience at CU ��«��Ƶ, also won a Director's New Innovator Award. (Read more about Donaldson's research.)

Off

Traditional

White

Some mother cells kick DNA damage 'down the road' to offspring

Anonymous — Wed, 07 Jun 2017 15:01:18 +0000

Some mother cells kick DNA damage 'down the road' to offspring Anonymous (not verified) Wed, 06/07/2017 - 09:01

A new ��«��Ƶ study has shown that some dividing human cells are “kicking the can down the road,” passing on low-level DNA damage to offspring, causing daughter cells to pause in a quiescent, or dormant, state previously thought to be random in origin.

Off

Traditional

White

Sabrina Spencer

Dr. Sabrina Spencer Shares Cancer Research Expertise with the Office of Science and Technology Policy White House Cabinet Director Dr. Arati Prabhakar

White House Science Official Comes to CU Anschutz for Cancer Briefing, Moonshot Updates

Arati Prabhakar, PhD, and a panel of elected officials and CU leaders shared information on the fight against cancer.

Off

Chroma awards Prof. Sabrina Spencer, PhD the Anne Heidenthal Prize for Fluorescence Research

Off

Biochemist wins $750k for novel cancer research

Off

Sabrina Spencer honored with a Provost Faculty Achievement Award

Off

To divide or not to divide? The mother cell may decide

Off

CU ��«����Ƶ attracts a record $631 million in annual research funding

Off

Biochemist wins top award for study of cellular proliferation

NIH’s High-Risk, High-Reward Research program to fund Sabrina Spencer’s CU ��«����Ƶ research that could shed light on cancer treatment

Off

Some mother cells kick DNA damage 'down the road' to offspring

Off

CU ��«��Ƶ attracts a record $631 million in annual research funding

NIH’s High-Risk, High-Reward Research program to fund Sabrina Spencer’s CU ��«��Ƶ research that could shed light on cancer treatment